Nanostructured morphology of a random P(DLLA-co-CL) copolymer
نویسندگان
چکیده
The random architecture of a commercial copolymer of poly(DL-lactic acid) and poly(ε-caprolactone), poly(DL-lactide-co-caprolactone), has been characterized by chemical structure analysis from hydrogen-1 nuclear magnetic resonance results. Moreover, spherical nanodomains have been detected in the thin films of this copolymer obtained after solvent evaporation. These nanodomains studied by atomic force microscopy and transmission elecron microscopy grow progressively under annealing until they collapse and form a homogenous disordered structure. This is the first time that the nanostructure of random poly(DL-lactic acid)/poly-(ε-caprolactone) copolymers is revealed, representing one of few experimental evidences on the possible nanostructuration of random copolymers.
منابع مشابه
Synthesis of a Nanostructured Molecularly Imprinted Acrylic acid-Based Network Copolymer as a Solid Sorbentforthe Quercetinextraction
A straightforward approach for the extraction of the quercetin was carried out by a nanoporous molecularly imprinted acrylic acid-based network copolymer as asolid sorbent. This technique involves a molecular template (quercetin) which is surrounded by functional monomers and are subsequently co-polymerized in the presence of an excess of the cross linkers. In this process, three-dimensional bi...
متن کاملIn vitro and in vivo degradation behavior of poly(trimethylene carbonate-co-d,l-lactic acid) copolymer
We present P(TMC-co-DLLA) copolymer with the molar ratio of TMC: DLLA = 15: 85 was used to systematic study of in vivo and in vitro degradation behaviors. Dense homogeneous copolymer specimens were prepared by compression molding method. The in vitro and in vivo degradation were, respectively, performed at simulative body condition and implanted into rat's subcutaneous condition. Investigations...
متن کاملBlends of Paclitaxel with POSS-Based Biodegradable Polyurethanes: Morphology, Miscibility, and Specific Interactions
The morphology, miscibility, and specific interactions of paclitaxel (PTx) with a family of polyhedral oligosilsesquioxane (POSS)-based biodegradable thermoplastic polyurethanes (POSS TPUs) were investigated systematically using wide-angle X-ray diffraction (WAXD), differential scanning calorimetry (DSC), and Fourier transform infrared spectroscopy (FTIR). These POSS TPUs incorporate an alterna...
متن کاملDesign of super-elastic biodegradable scaffolds with longitudinally oriented microchannels and optimization of the channel size for Schwann cell migration.
We newly designed super-elastic biodegradable scaffolds with longitudinally oriented microchannels for repair and regeneration of peripheral nerve defects. Four-armed poly(ε-caprolactone-co-D,L-lactide)s (P(CL-co-DLLA)s) were synthesized by ring-opening copolymerization of CL and DLLA from terminal hydroxyl groups of pentaerythritol, and acryloyl chloride was then reacted with the ends of the c...
متن کاملAmino-functionalized SBA-15 type mesoporous silica having nanostructured hexagonal platelet morphology.
Amino-functionalized SBA-15 type mesoporous silicas having unique hexagonal platelet morphologies with short channels (100-300 nm) running parallel to the thickness of the nanostructured hexagonal platelet type morphologies have been directly synthesized by co-condensation of aminopropyltriethoxysilane (APTES) and sodium metasilicate as a silica source in the presence of Pluronic P123 triblock ...
متن کامل